Why Is Important To Find The Best Ratio Of THC And CBD In Cannabis Strains

Human beings have been selectively growing and genetically manipulating the cannabis plant for nearly three thousand years. In that time it has been bred into thousands of strains with a nearly infinite array of cannabinoid and terpene profiles. Cannabinoids are what make the cannabis plant unique, they are a set of chemicals with vast medicinal potential for human beings, animals, and the cannabis plant itself. Terpenes are the flavor and scent chemicals that give everything in the world its own unique smell and taste.The cannabinoid and terpene profile of a strain matters because that is what makes it unique; if Sour Diesel didn’t have a lot of THC, CBG, myrcene, limonene, pinene, and caryophyllene it would not be Sour Diesel. Myrcene has been shown to weaken the blood-brain barrier to cannabinoids, raising the potency of high amounts of THC already present in Sour Diesel. Pinene is a bronchodilator, which increases the effectiveness of the lungs and bronchial passages allowing the user to smoke or vaporize more Sour Diesel without irritating their lungs.  

By paying attention to the cannabinoid and terpene profiles that work for them, patients can better know what sort of medicine to get in the future because they will know what worked in the past. For those who are not using cannabis medicinally, profiling matters because it lets you know what a strain will taste like and how high it will get you.Many people try to make generalizations about indica and sativa strains where often indicas are described as strains to make you sleepy and sativas are those that energize you, but these anecdotal views are not grounded in current science. Rather than talking about your cannabis in terms of it being indica or sativa dominant you are better off talking about the cannabinoid and terpene profile of that strain. Indica and sativa say more about what a plant looks like when it is growing than what its effects will be when consumed.

Given the fact that tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most prominent chemical compounds in the cannabis plant, the vast majority of research to date has focused on the ratio of these two cannabinoids. While the ability to control cannabinoid ratios within your own medicine remains limited, the information provided here will hopefully give you some insight into the future of cannabis based therapy. Research on the benefits of tetrahydrocannabinol (THC) and cannabidiol (CBD) in isolation is well established. THC demonstrates analgesic, anti-emetic, and anti-inflammatory properties, whereas CBD possesses anti-psychotic, anti-seizure, and anti-anxiety properties.

Every cannabinoid and terpene profile will produce different results and we are getting a better understanding of these results every day. Profiles that are heavily dominant in CBD, THCa, and CBG have been shown to be helpful to people suffering from epilepsy and other seizure conditions like Dravet or Doose Syndrome. As I have mentioned in previous posts, a balanced ratio of CBD and THC is ideal for anyone suffering from all types of pain, because both THC and CBD work to reduce pain through different mechanisms. CBD lowers the amount of pain felt and THC helps you forget that you are in pain; that means less pain signals are transmitted to your brain and when they are they feel less severe. People suffering from mood disorders such as PTSD, anxiety, or depression can see benefits from varying ratios, ranging from all THC to all CBD.

The CBD graduates the high of THC and reduces its adverse/side effects linked with psychosis. It keeps the experience more pleasant, while increasing relaxation it helps to find sleep within its natural cycle in contrary to other conventional prescribed drugs.

Ratio CBD:THC – Implications and Effects


  • Strong “high” psychotropic effect
    (especially over 30mg if ingested) Euphoria, uplifting mood, confused thought, uncontrolled laughs
  • Strong side Effects: Tachycardia, anxiety, tension…


  • Remarkable ‘high” effects Euphoria, laugh and thoughts more calm
  • Mild side effects: reduced risk of having tachycardia, anxiety, etc


  • Relaxation with very light “high” effects Little euphoria, calmness and tranquility
  • Few side effects


  • Little sedation and heaviness. Few to no “high” effects. No euphoria, sedation, light-headedness, dizziness
  • Practically no side effects


  • No “high” effect, at all. Ease up general mood. High therapeutic potential use: anti-psychotic, relaxing, used in epilepsy treatments
  • No side effects

There is no lethal dose with cannabis. Even though it’s a very safe drug, the patient has to experiment to determine their own dose. Just start slow and medicate step by step.

Different Ratios To Help Different Illness

1:1 CBD to THC – Targets certain cancers and helps other issues:

3:1 CBD to THC – Targets Auto-Immune Conditions:

20:1 CBD to THC – Targets Neurological isssues:

  • Anxiety
  • Cerebral Palsy
  • Depression
  • Epilepsy
  • Mild Arthritis
  • Parkinson’s
  • Restless Leg Syndrome
  • Phantom Pain
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